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Aortic root morphometry revisited-Clinical implications for aortic valve interventions.
- Source :
-
Clinical anatomy (New York, N.Y.) [Clin Anat] 2024 Apr 17. Date of Electronic Publication: 2024 Apr 17. - Publication Year :
- 2024
- Publisher :
- Ahead of Print
-
Abstract
- The complex anatomy of the aortic root is of great importance for many surgical and transcatheter cardiac procedures. Therefore, the aim of this study was to provide a comprehensive morphological description of the nondiseased aortic root. We morphometrically examined 200 autopsied human adult hearts (22.0% females, 47.9 ± 17.7 years). A meticulous macroscopic analysis of aortic root anatomy was performed. The largest cross-section area of the aortic root was observed in coaptation center plane (653.9 ± 196.5 mm <superscript>2</superscript> ), followed by tubular plane (427.7 ± 168.0 mm <superscript>2</superscript> ) and basal ring (362.7 ± 159.1 mm <superscript>2</superscript> ) (p < 0.001). The right coronary sinus was the largest (area: 234.3 ± 85.0 mm <superscript>2</superscript> ), followed by noncoronary sinus (218.7 ± 74.8 mm <superscript>2</superscript> ) and left coronary sinus (201.2 ± 78.08 mm <superscript>2</superscript> ). The noncoronary sinus was the deepest, followed by right and left coronary sinus (16.4 ± 3.2 vs. 15.9 ± 3.1 vs. 14.9 ± 2.9 mm, p < 0.001). In 68.5% of hearts, the coaptation center was located near the aortic geometric center. The left coronary ostium was located 15.6 ± 3.8 mm above sinus bottom (within the sinus in 91.5% and above sinutubular junction in 8.5%), while for right coronary ostium, it was 16.2 ± 3.5 mm above (83.5% within sinus and 16.5% above). In general, males exhibited larger aortic valve dimensions than females. A multiple forward stepwise regression model showed that anthropometric variables might predict the size of coaptation center plane (age, sex, and heart weight; R <superscript>2</superscript> = 31.8%), tubular plane (age and sex; R <superscript>2</superscript> = 25.6%), and basal ring (age and sex; R <superscript>2</superscript> = 16.9%). In conclusion, this study presents a comprehensive analysis of aortic-root morphometry and provides a platform for further research into the intricate interplay between structure and function of the aortic root.<br /> (© 2024 The Authors. Clinical Anatomy published by Wiley Periodicals LLC on behalf of American Association of Clinical Anatomists and British Association of Clinical Anatomists.)
Details
- Language :
- English
- ISSN :
- 1098-2353
- Database :
- MEDLINE
- Journal :
- Clinical anatomy (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 38630034
- Full Text :
- https://doi.org/10.1002/ca.24165