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Professionally applied fluorides for preventing and arresting dental caries in low- and middle-income countries: Systematic review.
- Source :
-
Journal of public health dentistry [J Public Health Dent] 2024 Jun; Vol. 84 (2), pp. 213-227. Date of Electronic Publication: 2024 Apr 16. - Publication Year :
- 2024
-
Abstract
- Objectives: This systematic review aimed to review the safety and effectiveness of professionally applied fluorides for preventing and arresting dental caries in low- and middle-income countries (LMICs).<br />Methods: Randomized controlled trials conducted in LMICs, in which professionally applied fluorides were compared with placebo/no treatment/health education only or usual care with a minimum one-year follow-up period, were included. Any topically applied fluoride agents such as sodium fluoride (NaF), acidulated phosphate fluoride, silver diamine fluoride (SDF), and nano silver fluoride (NSF) were included. Five databases (PubMed, Embase, Scopus, Web of Science, and Cochrane Library) were searched in May 2022. Meta-analysis was conducted using a random effect model.<br />Results: This review included 33 studies for qualitative synthesis, encompassing 16,375 children aged between 1.5 and 14 years. Nevertheless, the meta-analysis focused on only 17 studies, involving 4067 children. Fourteen papers assessed potential adverse events, none of which was reported as major adverse events. SDF and NSF were identified as effective in arresting caries on primary teeth (p < 0.05) compared with a placebo or no treatment. Fluoride varnish and gel were identified as effective in reducing new caries development on primary teeth (p < 0.05) but not on permanent teeth (p > 0.05). The certainty of the generated evidence obtained is low.<br />Conclusion: The review provides valuable insights into the use of professionally applied fluorides in LMICs and contributes to recommendations for their use. However, the limited rigorous evidence suggests the need for further research to strengthen these findings and draw more robust conclusions.<br /> (© 2024 The Authors. Journal of Public Health Dentistry published by Wiley Periodicals LLC on behalf of American Association of Public Health Dentistry.)
- Subjects :
- Humans
Child
Child, Preschool
Adolescent
Cariostatic Agents administration & dosage
Cariostatic Agents therapeutic use
Infant
Fluorides administration & dosage
Silver Compounds administration & dosage
Randomized Controlled Trials as Topic
Quaternary Ammonium Compounds administration & dosage
Dental Caries prevention & control
Developing Countries
Fluorides, Topical administration & dosage
Fluorides, Topical therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1752-7325
- Volume :
- 84
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of public health dentistry
- Publication Type :
- Academic Journal
- Accession number :
- 38623701
- Full Text :
- https://doi.org/10.1111/jphd.12617