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Dyslipidemia and associated factors among adult cardiac patients: a hospital-based comparative cross-sectional study.
- Source :
-
European journal of medical research [Eur J Med Res] 2024 Apr 15; Vol. 29 (1), pp. 237. Date of Electronic Publication: 2024 Apr 15. - Publication Year :
- 2024
-
Abstract
- Background: Atherosclerotic vascular diseases are a leading global cause of morbidity and mortality. Dyslipidemia, a major modifiable risk factor for cardiovascular disease, remains poorly understood among adult cardiac patients in in the study area. This study aims to determine the prevalence of dyslipidemia and identify associated factors in this population.<br />Methods: Hospital-based comparative cross-sectional study was conducted from May to August 2021. A total of 319 participants (153 cardiac cases, 166 healthy controls, aged ≥ 18) were included in the study. Socio-demographic, anthropometric, behavioral, and clinical data were collected using the WHO STEPS survey instrument through systematic sampling. Overnight fasting blood samples were obtained, and serum lipid profiles were analyzed using a COBAS 6000 analyzer. Data were analyzed with SPSS version 20.0, employing bivariable and multivariable logistic regression. Statistical significance was set at p < 0.05.<br />Results: The overall prevalence of dyslipidemia, encompassing at least one lipid abnormality, was 80.3% among 256 participants. Among cardiac cases, the prevalence rates were as follows: 72.5% for low HDL-cholesterol, 12.4% for hypercholesterolemia, 9.8% for elevated LDL-cholesterol, and 30.1% for hypertriglyceridemia. In controls, corresponding rates were 69.9%, 9.6%, 7.2%, and 32.5%. Significant factors linked to low HDL- cholesterol were female gender (AOR: 2.8, 95% CI 1.7-4.7) and obesity (AOR: 2.8, 95% CI 1.1-7.5). Abdominal obesity was associated with hypercholesterolemia (AOR: 5.2, 95% CI 1.9-14.3) and elevated LDL-cholesterol (AOR: 5.1, 95% CI 1.6-15.8). High blood pressure, overweight, and abdominal obesity were significantly linked to hypertriglyceridemia (p < 0.05).<br />Conclusion: Dyslipidemia was high among the study participants. Overweight, obesity, central adiposity, and high blood pressure were significantly associated with dyslipidemia in cardiac patients. This alarms the need for lipid profile assessment for patients periodically, with treatment follow-up to monitor any rising patterns and cardiovascular-related risks.<br /> (© 2024. The Author(s).)
- Subjects :
- Adult
Humans
Female
Male
Overweight complications
Overweight epidemiology
Cross-Sectional Studies
Obesity, Abdominal complications
Obesity, Abdominal epidemiology
Risk Factors
Obesity complications
Obesity epidemiology
Prevalence
Hospitals
Cholesterol
Lipids
Hypercholesterolemia complications
Hypercholesterolemia epidemiology
Dyslipidemias epidemiology
Dyslipidemias complications
Hypertension
Hypertriglyceridemia complications
Subjects
Details
- Language :
- English
- ISSN :
- 2047-783X
- Volume :
- 29
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- European journal of medical research
- Publication Type :
- Academic Journal
- Accession number :
- 38622622
- Full Text :
- https://doi.org/10.1186/s40001-024-01802-x