As-needed low-dose inhaled corticosteroid/formoterol therapy in patients with severe asthma included in the German Asthma Net cohort.

After the GINA update in 2019, the proportion of SMART therapy increased with evidence for better disease control in SMART patients compared to SABA alone https://bit.ly/3SSPX1C.
Competing Interests: Conflict of interest: C.A. Hinze has nothing to disclose. Conflict of interest: R. Ehmann has nothing to disclose. Conflict of interest: M. Jandl has nothing to disclose. Conflict of interest: K. Milger reports fees for lectures or consultation from AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Novartis and Sanofi, all outside the submitted work. Conflict of interest: O. Schmidt reports fees for lectures or consultations from AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Novartis and Sanofi, all outside the submitted work. Conflict of interest: C. Schulz reports fees for lectures or consultations from AstraZeneca, Novartis and Sanofi, all outside the submitted work. Conflict of interest: D. Skowasch reports fees for lectures or consultation from AstraZeneca, Boehringer Ingelheim, Chiesi, GSK, Janssen, MSD and Sanofi, all outside the submitted work. Conflict of interest: T. Welte and/or his institution received grants advisory/lecture/clinical trial fees and non-financial support from BMBF (German Ministry of Research and Education), AstraZeneca, GSK, Sanofi Aventis and Biotest, outside the submitted work. Conflict of interest: R. Buhl reports grants to Mainz University from Boehringer Ingelheim, GSK, Novartis, and Roche, as well as personal fees from AstraZeneca, Berlin-Chemie, Boehringer Ingelheim, Chiesi, Cipla, GSK, Novartis, Roche, Sanofi and Teva, all outside the submitted work. Conflict of interest: E. Hamelmann is funded by the BMBF (CHAMP, project number 01GL1742D) for characterisation of children and adolescents with severe asthma; he reports personal fees from ALK, Boehringer Ingelheim, GSK, Leti Pharma, Novartis, Nutricia, Sanofi and Stallergenes, all outside the submitted work. Conflict of interest: M. Idzko has received fees for lectures and/or advisory board meetings from Alk Pharma, AstraZeneca, Berlin-Chemie, Chiesi, CSL-Behring, Jansen & Jansen, Menarini, Novartis, Roche, Sanofi Aventis and Teva, all outside the submitted work. Conflict of interest: C. Taube has nothing to disclose. Conflict of interest: S. Korn has received fees for lectures and/or advisory board meetings from AstraZeneca, Chiesi, GSK, Novartis, Roche, Sanofi Aventis and Teva, all outside the submitted work. Conflict of interest: H. Suhling reports fees for lectures or consultation from AstraZeneca, GSK, Novartis and Sanofi, all outside the submitted work.
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