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Endoscopic-ultrasound-guided biliary drainage with placement of electrocautery-enhanced lumen-apposing metal stent for palliation of malignant biliary obstruction: Updated meta-analysis.
- Source :
-
World journal of gastrointestinal surgery [World J Gastrointest Surg] 2024 Mar 27; Vol. 16 (3), pp. 907-920. - Publication Year :
- 2024
-
Abstract
- Background: Endoscopic ultrasound-guided biliary drainage using electrocautery-enhanced (ECE) delivery of lumen-apposing metal stent (LAMS) is gradually being recognized as a viable palliative technique for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography (ERCP) failure. However, most of the studies that have assessed its efficacy and safety were small and heterogeneous. Prior meta-analyses of six or fewer studies that were published 2 years ago were therefore underpowered to yield convincing evidence.<br />Aim: To update the efficacy and safety of ECE-LAMS for treatment of biliary obstruction after ERCP failure.<br />Methods: We searched PubMed, EMBASE, and Scopus databases from the inception of the ECE technique to May 13, 2022. Primary outcome measure was pooled technical success rate, and secondary outcomes were pooled rates of clinical success, reintervention, and adverse events. Meta-analysis was performed using a random-effects model following Freeman-Tukey double-arcsine transformation in R software (version 4.1.3).<br />Results: Fourteen eligible studies involving 620 participants were ultimately included. The pooled rate of technical success was 96.7%, and clinical success was 91.0%. Adverse events were reported in 17.5% of patients. Overall reintervention rate was 7.3%. Subgroup analyses showed results were generally consistent.<br />Conclusion: ECE-LAMS has favorable success with acceptable adverse events in relieving biliary obstruction when ERCP is impossible. The consistency of results across most subgroups suggested that this is a generalizable approach.<br />Competing Interests: Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.<br /> (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1948-9366
- Volume :
- 16
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- World journal of gastrointestinal surgery
- Publication Type :
- Academic Journal
- Accession number :
- 38577086
- Full Text :
- https://doi.org/10.4240/wjgs.v16.i3.907