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Skeletal Transformations of Terpenoid Forskolin Employing an Oxidative Rearrangement Strategy.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2024 Apr 19; Vol. 89 (8), pp. 5741-5745. Date of Electronic Publication: 2024 Apr 03. - Publication Year :
- 2024
-
Abstract
- The skeletal transformations of diterpenoid forskolin were achieved by employing an oxidative rearrangement strategy. A library of 36 forskolin analogues with structural diversity was effectively generated. Computational analysis shows that 12 CTD compounds with unique scaffolds and ring systems were produced during the course of this work.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 89
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 38568052
- Full Text :
- https://doi.org/10.1021/acs.joc.4c00312