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O blood type is not associated with worse coagulopathy or outcome in exsanguinating trauma.
- Source :
-
American journal of surgery [Am J Surg] 2024 Aug; Vol. 234, pp. 117-121. Date of Electronic Publication: 2024 Mar 26. - Publication Year :
- 2024
-
Abstract
- Background: Despite improving understanding of trauma-induced coagulopathy (TIC), mortality and morbidity due to exsanguinating trauma remain high. Increased complications due to hemorrhage have been reported in blood group O, possibly due to reduced levels of von Willebrand factor (vWF).<br />Methods: An urban level 1 adult trauma center registry was retrospectively queried. Patients receiving ≥6 units of pRBC within 4 h of presentation were included. Patient demographics, admission labs and outcomes were obtained. Univariate and multiple logistic regression analyses were performed.<br />Results: 562 patients were identified. There were no significant differences in demographics, admission labs, or outcome between different ABO groups. After adjustment, Type A patients were more likely to be hypocoagulable compared to Type O patients (p = 0.014). No mortality differences were seen between ABO types in multiple regression analysis.<br />Conclusions: No outcome or mortality differences were seen between ABO types, therefore factors other than vWF expression should be considered to explain coagulopathy in trauma patients.<br />Competing Interests: Declaration of competing interest This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors have no conflicts of interest to disclose.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Male
Female
Retrospective Studies
Adult
Middle Aged
Trauma Centers statistics & numerical data
Registries
ABO Blood-Group System
Blood Coagulation Disorders etiology
Wounds and Injuries complications
Wounds and Injuries blood
Wounds and Injuries mortality
Exsanguination mortality
Exsanguination etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1883
- Volume :
- 234
- Database :
- MEDLINE
- Journal :
- American journal of surgery
- Publication Type :
- Academic Journal
- Accession number :
- 38553336
- Full Text :
- https://doi.org/10.1016/j.amjsurg.2024.03.021