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Myocardial injury after orbital atherectomy and its association with coronary lesion length.
- Source :
-
Cardiovascular revascularization medicine : including molecular interventions [Cardiovasc Revasc Med] 2024 Sep; Vol. 66, pp. 35-40. Date of Electronic Publication: 2024 Mar 24. - Publication Year :
- 2024
-
Abstract
- Background: Limited data are available regarding myocardial injury and its risk factors in percutaneous coronary interventions (PCI) of severe calcified lesions using orbital atherectomy (OA).<br />Methods: Patients who underwent OA at our institution were retrospectively enrolled into the present registry. High-sensitive Troponin I (hsTroponin I), EKG and echocardiography were used to assess myocardial injury after the procedure.<br />Results: A total of 27 patients between who underwent OA between January 2022 and June 2023 were included. Myocardial injury (elevation of hsTroponin I above the 99th percentile upper reference limit) occurred in all patients. Median hsTroponin I on the first day after the procedure was 1093 (557-4037) ng/l with a minimum of 86 ng/l and a maximum of 25,756 ng/l. Myocardial infarction occurred in two patients (7 %), who had severe coronary dissection after OA. Lesions were longer (47 [38-52] mm vs. 20 [14-47] mm; p = 0.009) in patients with hsTroponin I levels above the median compared to those with levels below. Furthermore, a moderate correlation between hsTroponin I and lesion length was detected (r = 0.54; p = 0.004).<br />Conclusions: In the present study myocardial injury occurred in all patients after OA without loss of viable myocardium in the majority of patients. Lesions length was found to be a significant factor associated with markedly increased hsTroponin I after the OA procedure.<br />Competing Interests: Declaration of competing interest There is no financial/personal interest regarding the present study.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Male
Female
Retrospective Studies
Aged
Risk Factors
Treatment Outcome
Middle Aged
Time Factors
Severity of Illness Index
Risk Assessment
Percutaneous Coronary Intervention adverse effects
Percutaneous Coronary Intervention instrumentation
Aged, 80 and over
Electrocardiography
Myocardial Infarction etiology
Myocardial Infarction diagnostic imaging
Atherectomy, Coronary adverse effects
Coronary Artery Disease diagnostic imaging
Coronary Artery Disease therapy
Troponin I blood
Biomarkers blood
Vascular Calcification diagnostic imaging
Vascular Calcification therapy
Registries
Subjects
Details
- Language :
- English
- ISSN :
- 1878-0938
- Volume :
- 66
- Database :
- MEDLINE
- Journal :
- Cardiovascular revascularization medicine : including molecular interventions
- Publication Type :
- Academic Journal
- Accession number :
- 38553275
- Full Text :
- https://doi.org/10.1016/j.carrev.2024.03.022