Chronic Coronary Disease in Older Adults.

The number of older adults age ≥75 with chronic coronary disease (CCD) continues to rise. CCD is a major contributor to morbidity, mortality, and disability in older adults. Older adults are underrepresented in randomized controlled trials of CCD, which limits generalizability to older adults living with multiple chronic conditions and geriatric syndromes. This review discusses the presentation of CCD in older adults, reviews the guideline-directed medical and invasive therapies, and recommends a patient-centric approach to making treatment decisions.
Competing Interests: Disclosure Drs E.S. Fishman and A.P. Ambrosini report no disclosures. A.A. Damluji: Dr A.A. Damluji receives research funding from the Pepper Scholars Program of the Johns Hopkins University Claude D. Pepper Older Americans Independence Center, United States funded by the National Institute on Aging P30-AG021334 and receives mentored patient-oriented research career development award from the National Heart, Lung, and Blood Institute, United States K23-HL153771 to 01. M.G. Nanna: Dr M.G. Nanna reports current research support from the American College of Cardiology Foundation, United States supported by the George F. and Ann Harris Bellows Foundation, the Patient-Centered Outcomes Research Institute, United States (PCORI), the Yale Claude D. Pepper Older Americans Independence Center (P30AG021342), and the National Institute on Aging/National Institutes of Health from R03AG074067 (GEMSSTAR award). Consulting from Heartflow, Inc, Merck.
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