The Effect of Surgical Procedure in the Nasal Cavity on the Passive Avoidance Conditioning and the Hypothalamic Level of Monoamines in Rats.

Authors :: Korolev AG
Kastyro IV
Inozemtsev AN
Latanov AV
Source :: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections [Dokl Biol Sci] 2024 Jun; Vol. 516 (1), pp. 27-31. Date of Electronic Publication: 2024 Mar 27.
Publication Year :: 2024
Abstract: A rat biological model of septoplasty was used to study the effect of surgery on passive avoidance conditioning (PAC). Septoplasty was shown to increase anxiety and to reduce exploratory activity in rodents during PAC. A neurochemical analysis of the hypothalamus was carried out immediately after the end of the experiment and showed an increase in norepinephrine (NE) metabolism after septoplasty. The finding was tentatively associated with activation of the hypothalamic-pituitary-adrenal axis.<br /> (© 2024. Pleiades Publishing, Ltd.)

Subjects :: Animals
Rats
Male
Norepinephrine metabolism
Rats, Wistar
Nasal Cavity metabolism
Nasal Cavity surgery
Hypothalamo-Hypophyseal System metabolism
Nasal Septum surgery
Nasal Septum metabolism
Avoidance Learning physiology
Hypothalamus metabolism

Language :: English
ISSN :: 1608-3105
Volume :: 516
Issue :: 1
Database :: MEDLINE
Journal :: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
Publication Type :: Academic Journal
Accession number :: 38538826
Full Text :: https://doi.org/10.1134/S0012496624700959

Full Text Access

Tools