Acute lymphoblastic leukemia with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse.

Authors :: Li R
Xia S
Liao Y
Zhou B
Source :: International journal of laboratory hematology [Int J Lab Hematol] 2024 Oct; Vol. 46 (5), pp. 766-767. Date of Electronic Publication: 2024 Mar 22.
Publication Year :: 2024
Abstract: Pseudo-Chediak-Higashi granules are large cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. However, pseudo-Chediak-Higashi granules are rarely found in acute lymphoblastic leukemia (ALL). We present the case of an 8-year-old boy who was diagnosed with ALL with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse, acting like a characteristic marker.<br /> (© 2024 John Wiley & Sons Ltd.)

Subjects :: Humans
Male
Child
Chediak-Higashi Syndrome diagnosis
Chediak-Higashi Syndrome pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma pathology
Cytoplasmic Granules pathology
Cytoplasmic Granules metabolism
Recurrence

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