Keratic Precipitates: An Overlooked Sign of Microsporidial Stromal Keratitis?

Authors :: Muni I
Priyadarshini SR
Sahu SK
Das S
Source :: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Nov; Vol. 32 (9), pp. 2261-2263. Date of Electronic Publication: 2024 Mar 21.
Publication Year :: 2024
Abstract: Purpose: To elucidate a distinctive clinical feature in cases of microsporidial stromal keratitis (MSK).<br />Method: A retrospective observational study of cases with a histopathological and/or microbiological diagnosis of MSK on corneal biopsy or host corneal button between 2016 and 2022 was conducted.<br />Results: Eighteen cases with a confirmed histopathological and/or microbiological diagnosis of MSK were detected. Careful review of slit-lamp photographs revealed the presence of pigmented keratic precipitates (KPs) beyond the area of stromal keratitis in five out of eighteen cases (27.7%).<br />Conclusion: The presence of pigmented KPs beyond the area of lesion can alert the clinician to keep microsporidia as a differential cause for stromal keratitis. Management can be tailored accordingly for a better outcome.