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Squamous cell carcinoma of the nasal vestibule in the Netherlands: A clinical and epidemiological review of 763 cases (2008-2021).
- Source :
-
Head & neck [Head Neck] 2024 Jul; Vol. 46 (7), pp. 1809-1821. Date of Electronic Publication: 2024 Mar 21. - Publication Year :
- 2024
-
Abstract
- Background: Squamous cell carcinoma of the nasal vestibule (SCCNV) is a rare disease, distinctly different in presentation, treatment, and outcome from squamous cell carcinoma (SCC) of the nasal cavity and paranasal sinuses. However, these are often not analyzed separately.<br />Methods: The Netherlands Cancer Registry (NCR) and pathology reports from the Dutch Nationwide Pathology Databank (PALGA) were used to identify all newly diagnosed SCCNV cases in the Netherlands between 2008 and 2021.<br />Results: A total of 763 patients were included. The yearly incidence rate displayed a significant downward trend with an annual percentage change (APC) of -3.9%. The 5-year overall survival (OS) and disease-free survival were 69.0% and 77.2%, respectively. The 5-year relative survival was 77.9% and improved slightly over the inclusion period. OS for patients who were staged cT3 appeared to be worse than those staged cT4a, calling the applicability of the TNM-classification into question.<br />Conclusion: SCC of the nasal vestibule is rare, with declining incidence rates. Introducing a specific topography code for SCCNV is recommended to enhance registration accuracy. The TNM classification seems poorly applicable to SCCNV, suggesting the need to explore alternative staging methods.<br /> (© 2024 The Authors. Head & Neck published by Wiley Periodicals LLC.)
- Subjects :
- Humans
Netherlands epidemiology
Male
Female
Aged
Middle Aged
Incidence
Adult
Aged, 80 and over
Neoplasm Staging
Disease-Free Survival
Survival Rate
Nose Neoplasms pathology
Nose Neoplasms epidemiology
Nose Neoplasms mortality
Nose Neoplasms therapy
Carcinoma, Squamous Cell pathology
Carcinoma, Squamous Cell epidemiology
Carcinoma, Squamous Cell mortality
Nasal Cavity pathology
Registries
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0347
- Volume :
- 46
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Head & neck
- Publication Type :
- Academic Journal
- Accession number :
- 38511478
- Full Text :
- https://doi.org/10.1002/hed.27749