Back to Search
Start Over
Survival and complications after carotid resection for head and neck squamous cell carcinoma: A systematic review and pooled analysis.
- Source :
-
Head & neck [Head Neck] 2024 Jul; Vol. 46 (7), pp. 1777-1787. Date of Electronic Publication: 2024 Mar 12. - Publication Year :
- 2024
-
Abstract
- Objective: The aim of this study is to analyze oncologic outcomes and complications rate after common or internal carotid artery (CCA/ICA) resection for head and neck squamous cell carcinoma (HNSCC).<br />Methods: This study was conducted in conformity with the PRISMA statement. A systematic review and pooled analysis was performed for overall survival (OS), disease specific survival (DSS) (primary outcomes), and perioperative death rate (secondary outcome).<br />Results: A total of 276 patients (males: 76.7%, n = 191/249) with a median age of 59 years (n = 239/276; 95% CI 55.0-61.7) who underwent CCA/ICA resection for HNSCC were included. The median follow-up time was 11 months (n = 276). Estimated pooled OS rates (95% CI) at 1 and 2 years were 52.7% (46.9-59.2) and 29.8% (24.3-36.5), respectively. The median OS (95% CI) was 14 months (12-17). Estimated pooled DSS rates (95% CI) at 1 and 2 years were 58.6% (52.7-65.2) and 34.6% (28.5-41.9), respectively. The median DSS (95% CI) was 16 months (14-19). The perioperative death rate was 6.9% (n = 19/276).<br />Conclusions: CCA/ICA resection should be considered as a treatment option for accurately selected patients. Multicentric prospective studies are recommended to develop a predictive score guiding the decision-making process.<br /> (© 2024 Wiley Periodicals LLC.)
- Subjects :
- Humans
Female
Carotid Artery, Internal surgery
Male
Middle Aged
Survival Rate
Carotid Artery, Common surgery
Head and Neck Neoplasms surgery
Head and Neck Neoplasms mortality
Squamous Cell Carcinoma of Head and Neck surgery
Squamous Cell Carcinoma of Head and Neck mortality
Postoperative Complications mortality
Postoperative Complications epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0347
- Volume :
- 46
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Head & neck
- Publication Type :
- Academic Journal
- Accession number :
- 38469988
- Full Text :
- https://doi.org/10.1002/hed.27723