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FCRL3 expression is upregulated and closely correlates with TIGIT expression in regulatory T cells of patients with systemic lupus erythematosus.

Authors :
Bahabayi A
Zhang YH
Yuan Z
Wang Y
Zhang Z
Zeng X
Guan Z
Wang P
Liu C
Source :
European journal of immunology [Eur J Immunol] 2024 May; Vol. 54 (5), pp. e2350739. Date of Electronic Publication: 2024 Mar 10.
Publication Year :
2024

Abstract

Using data from single-cell RNA sequencing and flow cytometry, we initially examined the expression of FCRL3, finding it to be elevated and positively associated with TIGIT expression in the regulatory T cells of patients with systemic lupus erythematosus. This also suggests that the co-expression of FCRL3 and TIGIT warrants further attention.<br /> (© 2024 Wiley‐VCH GmbH.)

Details

Language :
English
ISSN :
1521-4141
Volume :
54
Issue :
5
Database :
MEDLINE
Journal :
European journal of immunology
Publication Type :
Report
Accession number :
38461541
Full Text :
https://doi.org/10.1002/eji.202350739