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Pancreatic adenocarcinoma treated with surgical resection, toceranib phosphate and firocoxib in a dog: a case report.
- Source :
-
Veterinary research communications [Vet Res Commun] 2024 Jun; Vol. 48 (3), pp. 1921-1927. Date of Electronic Publication: 2024 Mar 08. - Publication Year :
- 2024
-
Abstract
- Exocrine pancreatic carcinomas are rarely reported in dogs. A ductal pancreatic adenocarcinoma in a 10-year-old intact beagle is described in this report. The diagnosis was made based on clinical signs, imaging (abdominal ultrasound and CT scan) and histopathology. Treatment consisted of partial right lobe pancreatectomy followed by adjuvant therapy with toceranib phosphate (Palladia®) and firocoxib (Previcox®) for six months. The treatment was well tolerated, and the survival time was 445 days. To our knowledge, this is the longest survival reported in the literature for a dog diagnosed with exocrine pancreatic adenocarcinoma. The results described here may contribute to provide a better understanding about this neoplasia and potential treatment options.<br /> (© 2024. The Author(s).)
- Subjects :
- Animals
Dogs
Adenocarcinoma veterinary
Adenocarcinoma drug therapy
Adenocarcinoma surgery
Pancreatectomy veterinary
Male
Antineoplastic Agents therapeutic use
Dog Diseases drug therapy
Dog Diseases surgery
Dog Diseases diagnostic imaging
Pancreatic Neoplasms veterinary
Pancreatic Neoplasms surgery
Pancreatic Neoplasms drug therapy
4-Butyrolactone analogs & derivatives
4-Butyrolactone therapeutic use
Indoles therapeutic use
Indoles administration & dosage
Pyrroles therapeutic use
Pyrroles administration & dosage
Sulfones therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1573-7446
- Volume :
- 48
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Veterinary research communications
- Publication Type :
- Academic Journal
- Accession number :
- 38453822
- Full Text :
- https://doi.org/10.1007/s11259-024-10349-5