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[Epilepsy and pregnancy].

Authors :
Gaus V
Ilyas-Feldmann M
Schmitz B
Source :
Der Nervenarzt [Nervenarzt] 2024 Apr; Vol. 95 (4), pp. 335-341. Date of Electronic Publication: 2024 Mar 07.
Publication Year :
2024

Abstract

Background: Regarding treatment of women of childbearing potential with epilepsy, several aspects of family planning and desire to have children have to be taken into account.<br />Objective: Overview of current data on mutual implications of epileptic seizures, antiseizure medication (ASM), pregnancy and child development.<br />Method: Review of the current literature, discussion and presentation of resulting treatment recommendations.<br />Results: Many ASMs bear the potential for clinically relevant interactions with both contraceptives and altered concentrations of sexual hormones and modified pharmacokinetics during pregnancy. All ASMs show an increased risk for congenital malformations; however, due to seizure-related risks for the mother and child effective ASM treatment during pregnancy is crucial.<br />Conclusion: When considering the special aspects of consultation and treatment of women of childbearing potential with epilepsy most pregnancies are uncomplicated.<br /> (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Details

Language :
German
ISSN :
1433-0407
Volume :
95
Issue :
4
Database :
MEDLINE
Journal :
Der Nervenarzt
Publication Type :
Academic Journal
Accession number :
38451327
Full Text :
https://doi.org/10.1007/s00115-024-01626-4