Reply to Kaestner et al.: Pioneering quantitative platforms for stored red blood cell assessment open the door for precision transfusion medicine.

Competing Interests: Competing interests statement:U.A.G. and Case Western Reserve University have financial interests in Hemex Health Inc. E.K., U.A.G., and Case Western Reserve University have financial interests in BioChip Labs Inc. U.A.G. and Case Western Reserve University have financial interests in Xatek Inc. U.A.G. has financial interests in DxNow Inc. Financial interests include licensed intellectual property, stock ownership, research funding, employment, and consulting. Hemex Health Inc. offers point-of-care diagnostics for hemoglobin disorders, anemia, and malaria. BioChip Labs Inc. offers commercial clinical microfluidic biomarker assays for inherited or acquired blood disorders. Xatek Inc. offers point-of-care global assays to evaluate the hemostatic process. DxNow Inc. offers microfluidic and bio-imaging technologies for in vitro fertilization, forensics, and diagnostics. Competing interests of Case Western Reserve University employees are overseen and managed by the Conflict of Interests Committee according to a Conflict-of-Interest Management Plan. The study was conducted prior to E.K. employment at IDEXX Laboratories, and the ideas expressed are not in his capacity as an IDEXX employee. A.D. serves on the Scientific Advisory Board of Hemanext Inc. and Macopharma Inc., and his competing interests are managed by the University of Colorado in accordance with their conflict-of-interest policies. S.N.T. and M.T. serve on the Scientific Advisory Board of Sylvatica Biotech Inc., a company focused on developing high subzero organ preservation technology. Competing interests for all authors affiliated with the Massachusetts General Hospital are managed by the MGH and Mass General Brigham in accordance with their conflict-of-interest policies. The remaining authors declare no competing interests.