The Use of Machine Learning in Eye Tracking Studies in Medical Imaging: A Review.

Machine learning (ML) has revolutionized medical image-based diagnostics. In this review, we cover a rapidly emerging field that can be potentially significantly impacted by ML - eye tracking in medical imaging. The review investigates the clinical, algorithmic, and hardware properties of the existing studies. In particular, it evaluates 1) the type of eye-tracking equipment used and how the equipment aligns with study aims; 2) the software required to record and process eye-tracking data, which often requires user interface development, and controller command and voice recording; 3) the ML methodology utilized depending on the anatomy of interest, gaze data representation, and target clinical application. The review concludes with a summary of recommendations for future studies, and confirms that the inclusion of gaze data broadens the ML applicability in Radiology from computer-aided diagnosis (CAD) to gaze-based image annotation, physicians' error detection, fatigue recognition, and other areas of potentially high research and clinical impact.