Disruption of the blood-brain barrier is correlated with spike endocytosis by ACE2 + endothelia in the CNS microvasculature in fatal COVID-19. Scientific commentary on "Detection of blood-brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2".

Authors :: Magro C
Tili E
Nuovo G
Source :: Acta neuropathologica [Acta Neuropathol] 2024 Feb 27; Vol. 147 (1), pp. 47. Date of Electronic Publication: 2024 Feb 27.
Publication Year :: 2024

Subjects :: Humans
Blood-Brain Barrier metabolism
Angiotensin-Converting Enzyme 2 metabolism
Brain metabolism
Endocytosis
Microvessels metabolism
Protein Binding
SARS-CoV-2
COVID-19

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