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Leniolisib: a novel treatment for activated phosphoinositide-3 kinase delta syndrome.

Authors :
De SK
Source :
Frontiers in pharmacology [Front Pharmacol] 2024 Feb 12; Vol. 15, pp. 1337436. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Publication Year :
2024

Abstract

IC <subscript>50</subscript> = 11 nM (PI3Kδ); 244 nM (PI3Kα); 424 nM (PI3Kβ), 2,230 nM (PI3Kγ).<br />Competing Interests: Author SD was employed by Conju-Probe. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.<br /> (Copyright © 2024 De.)

Details

Language :
English
ISSN :
1663-9812
Volume :
15
Database :
MEDLINE
Journal :
Frontiers in pharmacology
Publication Type :
Academic Journal
Accession number :
38410131
Full Text :
https://doi.org/10.3389/fphar.2024.1337436