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Impact of treatment guidelines and pivotal clinical trial results on a surgeon's decision regarding treatment for gastric cancer: a retrospective cohort study using the National Clinical Database.
- Source :
-
Surgery today [Surg Today] 2024 Sep; Vol. 54 (9), pp. 1084-1092. Date of Electronic Publication: 2024 Feb 24. - Publication Year :
- 2024
-
Abstract
- Purposes: The present study evaluated the impact of clinical guidelines for gastric cancer surgery on surgeons' choice of procedure in real-world practice. We focused on the 2014 guideline revision recommending laparoscopic surgery and the evidence concerning splenectomy for prophylactic lymphadenectomy reported in 2015 using the National Clinical Database, which is the most comprehensive database in Japan.<br />Methods: We investigated the monthly percentages of laparoscopic distal gastrectomies performed for stage I gastric cancer (LDG%) and splenectomies performed during total gastrectomy for advanced cancer (TGS%) between 2014 and 2017. We evaluated the descriptive statistics of the time-series changes in the LDG%, TGS%, and annual trends of outcomes.<br />Results: In total, 124,787 patients were enrolled. The mean LDG% and TGS% were 69.8% and 9.2%, respectively. The LDG% and TGS% were 66.4% and 16.7%, respectively, in January 2014 and 73.1% and 5.9%, respectively, in December 2017. LDG% consistently increased, and TGS% showed a consistent downward trend throughout the observation period. There was no significant change in this trend after the publication of the guideline recommendations or clinical trial results.<br />Conclusion: No significant changes in surgical procedures were observed after publication of the guidelines or results of clinical trials.<br /> (© 2024. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd.)
- Subjects :
- Humans
Retrospective Studies
Databases, Factual
Splenectomy methods
Japan
Surgeons
Clinical Trials as Topic
Female
Male
Cohort Studies
Neoplasm Staging
Clinical Decision-Making
Middle Aged
Aged
Stomach Neoplasms surgery
Gastrectomy methods
Practice Guidelines as Topic
Laparoscopy methods
Lymph Node Excision
Subjects
Details
- Language :
- English
- ISSN :
- 1436-2813
- Volume :
- 54
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Surgery today
- Publication Type :
- Academic Journal
- Accession number :
- 38402328
- Full Text :
- https://doi.org/10.1007/s00595-024-02814-0