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A Rare Case of Complete-Immunotherapy-Responsive Metastatic Non-Small Cell Lung Cancer with Long Lasting Progression-Free Survival: A Case Report.

Authors :
De Intinis C
Izzo P
Codacci-Pisanelli M
Izzo L
Messineo D
Sibio S
Campagnol M
Lai S
Molle M
Izzo S
Source :
Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Jan 26; Vol. 31 (2), pp. 723-732. Date of Electronic Publication: 2024 Jan 26.
Publication Year :
2024

Abstract

Background and Introduction: Lung cancer is a prevalent and deadly disease globally. Non-small cell lung cancer (NSCLC) is the most common subtype, comprising 85% of cases.<br />Case Report: A 65-year-old male ex-smoker presented to our facility with a nocturnal cough. Various investigations revealed that he had metastatic NSCLC, for which he underwent chemotherapy with cisplatin and gemcitabine, followed by immunotherapy with Nivolumab. He achieved a complete response to the therapy and has remained free from recurrence for over 7 years since the initial diagnosis.<br />Discussion and Conclusions: The treatment of metastatic NSCLC remains a significant therapeutic challenge, but the implementation of new therapeutic techniques has expanded the possibilities of achieving complete and durable eradication of the disease.

Details

Language :
English
ISSN :
1718-7729
Volume :
31
Issue :
2
Database :
MEDLINE
Journal :
Current oncology (Toronto, Ont.)
Publication Type :
Academic Journal
Accession number :
38392047
Full Text :
https://doi.org/10.3390/curroncol31020053