Back to Search
Start Over
Tranexamic acid decreases transfusion requirements during the modified pi-plasty procedure for sagittal craniosynostosis.
- Source :
-
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2024 May; Vol. 52 (5), pp. 619-621. Date of Electronic Publication: 2024 Feb 13. - Publication Year :
- 2024
-
Abstract
- The aim of our study was to evaluate the effectiveness of intraoperative tranexamic acid (TXA) administration in decreasing transfusion needs in patients undergoing modified pi-plasty. A retrospective study was performed using a population of 59 patients who underwent modified pi-plasty, wherein patients who received TXA during surgery (study group, n = 26) were compared with patients who did not receive TXA (control group, n = 33). The primary study endpoints were intraoperative red blood cell substitution (%), postoperative red blood cell substitution (%), total red blood cell substitution (%), and hematocrit variation. Perioperative administration of TXA significantly decreased the total red blood cell substitution (62.90% vs 86.70%; p = 0.002) and resulted in a higher postoperative hematocrit (29.47% vs 27.53%; p = 0.060). In conclusion, perioperative administration of TXA significantly decreased blood transfusion requirements in patients with sagittal craniosynostosis undergoing modified pi-plasty.<br /> (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1878-4119
- Volume :
- 52
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 38378370
- Full Text :
- https://doi.org/10.1016/j.jcms.2024.02.024