Targeting LGR4-Wnt activates ferroptosis and reverses drug resistance in colorectal cancer.

Subjects

Subjects :

Humans
Wnt Signaling Pathway drug effects
Cell Line, Tumor
Animals
Mice
Colorectal Neoplasms drug therapy
Colorectal Neoplasms metabolism
Ferroptosis drug effects
Drug Resistance, Neoplasm
Receptors, G-Protein-Coupled metabolism

Details

Language :

English

ISSN :

2662-1347

Volume :

5

Issue :

4

Database :

MEDLINE

Journal :

Nature cancer

Publication Type :

Academic Journal

Accession number :

38355778

Full Text :

https://doi.org/10.1038/s43018-023-00714-9