Cryptococcus neoformans Infections Differ Among Human Immunodeficiency Virus (HIV)-Seropositive and HIV-Seronegative Individuals: Results From a Nationwide Surveillance Program in France.

Authors :: Paccoud O
Desnos-Ollivier M
Cassaing S
Boukris-Sitbon K
Alanio A
Bellanger AP
Bonnal C
Bonhomme J
Botterel F
Bougnoux ME
Brun S
Chouaki T
Cornet M
Dannaoui E
Demar M
Desbois-Nogard N
Durieux MF
Favennec L
Fekkar A
Gabriel F
Gangneux JP
Guitard J
Hasseine L
Huguenin A
Le Gal S
Letscher-Bru V
Mahinc C
Morio F
Nicolas M
Rouges C
Cateau E
Persat F
Poirier P
Ranque S
Roosen G
Roux AL
Sasso M
Lortholary O
Lanternier F
Source :: Open forum infectious diseases [Open Forum Infect Dis] 2023 Dec 22; Vol. 11 (2), pp. ofad658. Date of Electronic Publication: 2023 Dec 22 (Print Publication: 2024).
Publication Year :: 2023
Abstract: Among 1107 cryptococcosis cases from the French surveillance network (2005-2020), the proportion of HIV-seronegative individuals has recently surpassed that of HIV-seropositive individuals. We observed marked differences in patient characteristics, disease presentations, cryptococcal antigen results, infecting species, and mortality according to HIV serostatus.<br />Competing Interests: Potential conflicts of interest. Over the past 5 years, E. D. has received research grants from MSD, Gilead, and bioMérieux; travel grants from Gilead, MSD, and Pfizer; and speaker's fees from Gilead and Pfizer. All other authors report no potential conflicts of interest.<br /> (© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

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