The omicron BA.2.86 subvariant as a new serotype of SARS-CoV-2.

Competing Interests: We declare no competing interests. PD, CW, and SH contributed equally to this work. This work was supported by the National Key R&D Program of China (2022YFC2303403), the National Natural Science Foundation of China (82225021, 92269203, and 32171428), and Chinese Academy of Sciences (CAS) Young Scientists in Basic Research (YSBR-010). We thank Prof Xin Zhao for sharing the plasmids used to prepare the pseudotyped viruses. We thank the Laboratory Animal Center at the Institute of Zoology, CAS, and the Institutional Center for Shared Technology and Facilities at the Institute of Microbiology, CAS. QW and GFG initiated and coordinated the project. GFG, QW, and PD designed the experiments. CW and SH constructed the plasmids, prepared the mRNA vaccines, and performed neutralisation assays with RF to prepare the pseudotyped viruses. SH performed animal experiments. PD, CW, and SH analysed the data. PD wrote the manuscript. QW and GFG revised the manuscript.