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IFNγ: Priming for death.

Authors :
Vince JE
Source :
The Journal of cell biology [J Cell Biol] 2024 Mar 04; Vol. 223 (3). Date of Electronic Publication: 2024 Feb 08.
Publication Year :
2024

Abstract

TNF signaling does not result in cell death unless multiple inhibitory signals are overcome, which can be accomplished by simultaneous signaling through IFNγ. In this issue, Deng and colleagues (http://doi.org/10.1083/jcb.202305026) dissect the mechanisms by which IFNγ signaling combines with TNF to mediate cell death through caspase-8, discussed by James E. Vince.<br /> (© 2024 Vince.)

Details

Language :
English
ISSN :
1540-8140
Volume :
223
Issue :
3
Database :
MEDLINE
Journal :
The Journal of cell biology
Publication Type :
Academic Journal
Accession number :
38329462
Full Text :
https://doi.org/10.1083/jcb.202401127