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The effect of the size of gold nanoparticle contrast agents on CT imaging of the gastrointestinal tract and inflammatory bowel disease.

Authors :
Rosario-BerrĂ­os DN
Pang A
Liu LP
Maidment PSN
Kim J
Yoon S
Nieves LM
Mossburg K
Adezio A
Noel P
Lennon EM
Cormode DP
Source :
BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 23. Date of Electronic Publication: 2024 Jan 23.
Publication Year :
2024

Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). CT imaging with contrast agents is commonly used for visualizing the gastrointestinal (GI) tract in UC patients. CT is a common imaging modality for evaluating IBD, especially in patients with acute abdominal pain presenting to emergency departments. CT's major limitation lies in its lack of specificity for imaging UC, as the commonly used agents are not well-suited for inflamed areas. Recent studies gastrointestinal tract (GIT) in UC. Further systemic research is needed to explore novel contrast agents that can specifically image disease processes in this disease setting.

Details

Language :
English
Database :
MEDLINE
Journal :
BioRxiv : the preprint server for biology
Accession number :
38328034
Full Text :
https://doi.org/10.1101/2024.01.20.576354