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[A Case of Long-Term Survival with Metachronous Hepatic and Pulmonary Metastases from Transverse Colon Cancer by Multidisciplinary Treatment].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2023 Dec; Vol. 50 (13), pp. 1857-1859. - Publication Year :
- 2023
-
Abstract
- A 64-year-old woman underwent right hemicolectomy for transverse colon cancer. Histopathological findings revealed T, type 2, 24×22 mm, tub2, pT2N1a(1/23)M0, and pStage Ⅲa. Postoperative adjuvant chemotherapy was not administered at the patient's request. One year after surgery, carcinoembryonic antigen(CEA)level was elevated, and Gd-EOB-DTPA- enhanced MRI revealed a nodule in segment 2 and 4/8 of the liver. Based on the diagnosis of hepatic metastasis, laparoscopic partial hepatectomy was performed. Three years after hepatectomy, CEA level was found to be elevated again, and chest CT showed a solitary pulmonary nodule in segment 7 of the right lung. With a diagnosis as pulmonary metastasis, FOLFIRI plus bevacizumab was performed. After 41 courses of FOLFIRI plus bevacizumab, the pulmonary nodule decreased in size, and no new lesions appeared. The chemotherapy was terminated at the patient's request. Six months later, the pulmonary nodule increased in size, and thoracoscopic partial pulmonary resection was performed. Hepatic and pulmonary resection specimens were histopathologically consistent as metastasis of colorectal cancer. The patient has been alive without recurrence for about 4 years after final surgery(pulmonary resection)without postoperative adjuvant chemotherapy. We report a case of long-term survival with metachronous hepatic and pulmonary metastases from transverse colon cancer by multidisciplinary treatment.
- Subjects :
- Female
Humans
Middle Aged
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Bevacizumab therapeutic use
Carcinoembryonic Antigen metabolism
Hepatectomy
Liver pathology
Colon, Transverse surgery
Colon, Transverse pathology
Colonic Neoplasms drug therapy
Colonic Neoplasms surgery
Colonic Neoplasms pathology
Liver Neoplasms drug therapy
Liver Neoplasms surgery
Liver Neoplasms secondary
Lung Neoplasms drug therapy
Lung Neoplasms surgery
Lung Neoplasms secondary
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 50
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 38303231