Back to Search
Start Over
The mediodorsal thalamus in executive control.
The mediodorsal thalamus in executive control.
- Source :
-
Neuron [Neuron] 2024 Mar 20; Vol. 112 (6), pp. 893-908. Date of Electronic Publication: 2024 Jan 30. - Publication Year :
- 2024
-
Abstract
- Executive control, the ability to organize thoughts and action plans in real time, is a defining feature of higher cognition. Classical theories have emphasized cortical contributions to this process, but recent studies have reinvigorated interest in the role of the thalamus. Although it is well established that local thalamic damage diminishes cognitive capacity, such observations have been difficult to inform functional models. Recent progress in experimental techniques is beginning to enrich our understanding of the anatomical, physiological, and computational substrates underlying thalamic engagement in executive control. In this review, we discuss this progress and particularly focus on the mediodorsal thalamus, which regulates the activity within and across frontal cortical areas. We end with a synthesis that highlights frontal thalamocortical interactions in cognitive computations and discusses its functional implications in normal and pathological conditions.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1097-4199
- Volume :
- 112
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Neuron
- Publication Type :
- Academic Journal
- Accession number :
- 38295791
- Full Text :
- https://doi.org/10.1016/j.neuron.2024.01.002