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Cytogenetic analyses in 89 patients with secondary hematologic disorders--results of a cooperative study.
- Source :
-
Cancer genetics and cytogenetics [Cancer Genet Cytogenet] 1987 May; Vol. 26 (1), pp. 65-74. - Publication Year :
- 1987
-
Abstract
- Eighty-nine patients who developed a secondary hematologic disorder and were studied with chromosome analysis were collected from nine institutions. The results of the study confirmed previous findings, in particular, -5/5q-, -7/7q-, -17, and +21 were the most frequently encountered aberrations. Moreover, a t(1;7)(p11;p11) was reported in four cases and consistent chromosome abnormalities were observed in a small group of patients who had been treated only with surgery, but not with chemo- or radiotherapy for a previous tumor.
- Subjects :
- Acute Disease
Adolescent
Adult
Aged
Antineoplastic Agents adverse effects
Antineoplastic Agents therapeutic use
Carcinoma genetics
Carcinoma therapy
Female
Humans
Karyotyping
Leukemia chemically induced
Leukemia, Radiation-Induced genetics
Male
Middle Aged
Myelodysplastic Syndromes chemically induced
Myelodysplastic Syndromes etiology
Neoplasms genetics
Radiation Injuries etiology
Radiation Injuries genetics
Chromosome Aberrations
Leukemia genetics
Myelodysplastic Syndromes genetics
Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0165-4608
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cancer genetics and cytogenetics
- Publication Type :
- Academic Journal
- Accession number :
- 3828975
- Full Text :
- https://doi.org/10.1016/0165-4608(87)90134-8