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Levofloxacin-Induced Hepatotoxicity in Patients With Legionnaires' Disease: Implications and Management.

Authors :
Ismail M
Parikh N
Zhai M
Elaskandrany MA
Wang W
Source :
Cureus [Cureus] 2023 Dec 28; Vol. 15 (12), pp. e51248. Date of Electronic Publication: 2023 Dec 28 (Print Publication: 2023).
Publication Year :
2023

Abstract

Legionnaires' disease (LD), caused by the Legionella bacterium, primarily manifests as pneumonia and could result in a spectrum of clinical severity. As treatment necessitates the use of antibiotics, levofloxacin, a fluoroquinolone, is a commonly preferred option due to its broad-spectrum activity. However, the potential side effects of levofloxacin, including rare instances of hepatotoxicity, introduce a therapeutic challenge. This case report explores the association between levofloxacin and hepatotoxicity and its implications for treating LD.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2023, Ismail et al.)

Details

Language :
English
ISSN :
2168-8184
Volume :
15
Issue :
12
Database :
MEDLINE
Journal :
Cureus
Publication Type :
Report
Accession number :
38283526
Full Text :
https://doi.org/10.7759/cureus.51248