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Molecular epidemiology of pregnancy using omics data: advances, success stories, and challenges.

Authors :
Rahnavard A
Chatterjee R
Wen H
Gaylord C
Mugusi S
Klatt KC
Smith ER
Source :
Journal of translational medicine [J Transl Med] 2024 Jan 26; Vol. 22 (1), pp. 106. Date of Electronic Publication: 2024 Jan 26.
Publication Year :
2024

Abstract

Multi-omics approaches have been successfully applied to investigate pregnancy and health outcomes at a molecular and genetic level in several studies. As omics technologies advance, research areas are open to study further. Here we discuss overall trends and examples of successfully using omics technologies and techniques (e.g., genomics, proteomics, metabolomics, and metagenomics) to investigate the molecular epidemiology of pregnancy. In addition, we outline omics applications and study characteristics of pregnancy for understanding fundamental biology, causal health, and physiological relationships, risk and prediction modeling, diagnostics, and correlations.<br /> (© 2024. The Author(s).)

Details

Language :
English
ISSN :
1479-5876
Volume :
22
Issue :
1
Database :
MEDLINE
Journal :
Journal of translational medicine
Publication Type :
Academic Journal
Accession number :
38279125
Full Text :
https://doi.org/10.1186/s12967-024-04876-7