Detection and Scoring of Extracorporeal Circuit Clotting During Hemodialysis.

Authors :: Vanommeslaeghe F
Van Biesen W
François K
Source :: Seminars in nephrology [Semin Nephrol] 2023 Nov; Vol. 43 (6), pp. 151474. Date of Electronic Publication: 2024 Jan 24.
Publication Year :: 2023
Abstract: Maintaining patency of the extracorporeal hemodialysis (HD) circuit is a prerequisite to perform HD. Unfractionated heparin and low-molecular-weight heparins are the most used anticoagulants in maintenance HD, but their administration comes with a major trade-off of bleeding complications. This narrative review article discusses technical factors impacting on HD circuit patency, such as tubings, dialyzer membranes, priming practices, and treatment settings. Strategies for monitoring extracorporeal circuit clotting during and after treatment are also reviewed, as these are essential tools for optimizing anticoagulation.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)