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The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction.

Authors :
Hazan H
Ferrara M
Riley S
Li F
Zhou B
Kline E
Gibbs-Dean T
Karmani S
Tayfur SN
Tek C
Keshavan M
Srihari V
Source :
Schizophrenia research [Schizophr Res] 2024 Feb; Vol. 264, pp. 457-461. Date of Electronic Publication: 2024 Jan 23.
Publication Year :
2024

Abstract

We examined the effects of an early detection (ED) campaign (Mindmap), that successfully shortened the duration of untreated psychosis (DUP), on patient presentation profiles at two receiving coordinated specialty care (CSC) services. Data were collected between 2015 and 2019 during a test of ED delivered at one CSC (STEP, n = 147) compared to usual detection at another CSC (PREP, n = 63). Regression models were used to test the effects of ED and DUP on presentation. Before the launch of ED, there were no differences in presentation between STEP and PREP. However, the ED changed the profile of presentations to STEP such that patients were admitted with better negative and total symptoms scores, but worse GAF current and GAF social and with a greater decline in function over the prior year (GAF-Δ). Site-by-time interaction effects were not significant. During the campaign years, STEP vs. PREP recruited patients with better negative and total symptoms, GAF role, and pre-morbid adjustment scores but with worse positive symptoms, GAF current, and GAF-Δ. Nonetheless, mediation analysis revealed that DUP reduction accounted for very little (<8 %) of these differences in presentation. Early detection campaigns while successfully reducing access delays, can have salutary effects on presentation independent of DUP reduction.<br />Competing Interests: Declaration of competing interest None of the authors have any conflicts of interest of financial support to report.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1573-2509
Volume :
264
Database :
MEDLINE
Journal :
Schizophrenia research
Publication Type :
Academic Journal
Accession number :
38266513
Full Text :
https://doi.org/10.1016/j.schres.2024.01.022