What trials do and do not tell us about treatments for severe asthma.

Competing Interests: JKQ has been supported by institutional research grants from the Industrial Strategy Challenge Fund, the Medical Research Council, Health Data Research, GSK, Boehringer Ingelheim, Asthma + Lung UK, and AstraZeneca, and has received personal fees for advisory board participation, consultancy, or speaking fees from GlaxoSmithKline, Evidera, Chiesi, AstraZeneca, and Insmed, unrelated to the topic of this Comment. PLS declares no competing interests.