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Generation of induced pluripotent stem cell line (MIPTi002-A) derived from a patient with a heterozygous type mutation in the CDC73 gene.

Authors :
Alsalloum A
Asaad W
Krupinova J
Kegeles E
Sirotkina P
Panova A
Mityaeva O
Volchkov P
Source :
Stem cell research [Stem Cell Res] 2024 Mar; Vol. 75, pp. 103311. Date of Electronic Publication: 2024 Jan 10.
Publication Year :
2024

Abstract

CDC73-related disorders are inherited in an autosomal dominant manner. An individual with a CDC73-related disorder may have inherited the disorder from an affected parent or developed it as the result of a de novo pathogenic variant of CDC73. The iPSC line was obtained by reprogramming the PBMCs of a patient with a heterozygous type mutation of the CDC73 gene. This cell line could be useful to scrutinize and study the development of CDC73-associated parathyroid carcinoma.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024. Published by Elsevier B.V.)

Details

Language :
English
ISSN :
1876-7753
Volume :
75
Database :
MEDLINE
Journal :
Stem cell research
Publication Type :
Academic Journal
Accession number :
38237426
Full Text :
https://doi.org/10.1016/j.scr.2024.103311