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SARS-CoV-2 biology and host interactions.
- Source :
-
Nature reviews. Microbiology [Nat Rev Microbiol] 2024 Apr; Vol. 22 (4), pp. 206-225. Date of Electronic Publication: 2024 Jan 15. - Publication Year :
- 2024
-
Abstract
- The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected our society. The rapid spread and continuous evolution of new SARS-CoV-2 variants continue to threaten global public health. Recent scientific advances have dissected many of the molecular and cellular mechanisms involved in coronavirus infections, and large-scale screens have uncovered novel host-cell factors that are vitally important for the virus life cycle. In this Review, we provide an updated summary of the SARS-CoV-2 life cycle, gene function and virus-host interactions, including recent landmark findings on general aspects of coronavirus biology and newly discovered host factors necessary for virus replication.<br /> (© 2024. Springer Nature Limited.)
- Subjects :
- Humans
Virus Replication
Biology
SARS-CoV-2 genetics
COVID-19
Subjects
Details
- Language :
- English
- ISSN :
- 1740-1534
- Volume :
- 22
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Nature reviews. Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 38225365
- Full Text :
- https://doi.org/10.1038/s41579-023-01003-z