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Impact of COVID-19 pandemic on healthcare delivery for lysosomal storage disorders at a tertiary care public hospital in Mumbai.
- Source :
-
Journal of postgraduate medicine [J Postgrad Med] 2024 Jan-Mar; Vol. 70 (1), pp. 23-28. - Publication Year :
- 2024
-
Abstract
- Introduction: Management of lysosomal storage disorders (LSDs) requires periodic visits for medical surveillance and hospitalizations. Management of LSDs may have been adversely impacted during the COVID-19 pandemic.<br />Objective: To identify the factors impacting health care for patients with LSDs during the COVID-19 pandemic.<br />Methods: An observational study was conducted in Mumbai comparing infusion practices and reasons for missed infusions for 15 months before March 2020 versus two phases during the pandemic (April 2020-March 2021 and April 2021-March 2022) in patients receiving intravenous enzyme replacement therapy (ERT) and on oral substrate reduction therapy (SRT).<br />Results: Fifteen patients with LSDs were enrolled. Before the pandemic, 6/13 (46%) were receiving ERT at the study site, 4/13 (31%) at a local hospital, and 3/13 (23%) at home; two were on SRT. The median distance traveled for receiving ERT was 37 km, and 4.4 infusions/patient were missed. From April 2020 to March 2021, two more patients opted for home ERT infusions. The median distance traveled for receiving ERT was 37 km, and 11.6 infusions/patient were missed. From April 2021 to March 2022, one more patient opted for home ERT infusions. The median distance traveled for receiving ERT was 7 km, and 5.6 infusions/patient were missed. The pandemic also affected SRT compliance adversely. For all patients, the cause of disrupted treatment was travel curbs (69%) and fear of getting COVID-19 infection (38%).<br />Conclusions: Treatment of LSDs was disrupted during the pandemic, with an increase in missed ERT infusions and SRT doses.
Details
- Language :
- English
- ISSN :
- 0972-2823
- Volume :
- 70
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of postgraduate medicine
- Publication Type :
- Academic Journal
- Accession number :
- 38197333
- Full Text :
- https://doi.org/10.4103/jpgm.jpgm_705_23