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Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine.
- Source :
-
Briefings in bioinformatics [Brief Bioinform] 2023 Nov 22; Vol. 25 (1). - Publication Year :
- 2023
-
Abstract
- Network pharmacology (NP) provides a new methodological perspective for understanding traditional medicine from a holistic perspective, giving rise to frontiers such as traditional Chinese medicine network pharmacology (TCM-NP). With the development of artificial intelligence (AI) technology, it is key for NP to develop network-based AI methods to reveal the treatment mechanism of complex diseases from massive omics data. In this review, focusing on the TCM-NP, we summarize involved AI methods into three categories: network relationship mining, network target positioning and network target navigating, and present the typical application of TCM-NP in uncovering biological basis and clinical value of Cold/Hot syndromes. Collectively, our review provides researchers with an innovative overview of the methodological progress of NP and its application in TCM from the AI perspective.<br /> (© The Author(s) 2024. Published by Oxford University Press.)
Details
- Language :
- English
- ISSN :
- 1477-4054
- Volume :
- 25
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Briefings in bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 38197310
- Full Text :
- https://doi.org/10.1093/bib/bbad518