Novel small-molecule inhibitors of SARS-CoV-2 main protease with nanomolar antiviral potency.

Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Suzhou Ark Biopharmaceutical Co., Ltd. is the inventor of the six investigated small molecules in this study and the holder of the corresponding patent (international patent application number: PCT/CN 2022/143566; international patent publication number: WO2023/125846 A1).