Review of reinforcement learning applications in segmentation, chemotherapy, and radiotherapy of cancer.

Owing to early diagnosis and treatment of cancer as a prerequisite in recent times, the role of machine learning has been increased substantially. The mathematically powerful and optimized solutions for the detection and cure of cancer are constantly being explored and novel models based upon standard algorithms are also being developed. Leveraging one such solution is Reinforcement Learning (RL), which is a semi-supervised type of learning. The paper presents a detailed discussion on the various RL techniques, algorithms, and open issues, in addition to the review of literature for diagnosis and treatment of cancer. A smaller number of publications for diagnosis and treatment of cancer have been reported before 2011 but now after the success of Deep Learning (DL) and the advent of Deep Reinforcement Learning (DRL), the publications have grown in number from 2017 onwards. The scope of RL for cancer diagnosis and treatment is also demystified and provides the research community with the insights of how to formulate RL problem as a Cancer diagnostic problem. RL has been found successful for landmark detection in medical images and optimal control of drugs and radiations.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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