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Clinical Use of Adrenergic Receptor Ligands in Acute Care Settings.

Authors :
Langnas E
Maze M
Source :
Handbook of experimental pharmacology [Handb Exp Pharmacol] 2024; Vol. 285, pp. 617-637.
Publication Year :
2024

Abstract

In this chapter, we review how ligands, both agonists and antagonists, for the major classes of adrenoreceptors, are utilized in acute care clinical settings. Adrenergic ligands exert their effects by interacting with the three major classes of adrenoceptors. Adrenoceptor agonists and antagonists have important applications, ranging from treatment of hypotension to asthma, and have proven to be extremely useful in a variety of clinical settings of acute care from the operating room to the critical care environment. Continued research interpreting the mechanisms of adrenoreceptors may help the discovery of new drugs with more desirable clinical profiles.<br /> (© 2024. The Author(s), under exclusive license to Springer Nature Switzerland AG.)

Details

Language :
English
ISSN :
0171-2004
Volume :
285
Database :
MEDLINE
Journal :
Handbook of experimental pharmacology
Publication Type :
Academic Journal
Accession number :
38177400
Full Text :
https://doi.org/10.1007/164_2023_705