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H 2 S serves as the immunoregulatory essence of apoptotic cell death.
- Source :
-
Cell metabolism [Cell Metab] 2024 Jan 02; Vol. 36 (1), pp. 3-5. - Publication Year :
- 2024
-
Abstract
- Apoptosis supports tissue homeostasis and prevents immune disorders by removing damaged and functionally aberrant cells. Here, Ou et al. utilized genetic, pharmacological, and proteomic approaches focused on sulfur amino acid catabolism to discover that hydrogen sulfide (H <subscript>2</subscript> S) release during apoptosis suppresses Th17 cell differentiation, thus providing therapeutic targets for autoimmune diseases.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1932-7420
- Volume :
- 36
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cell metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 38171337
- Full Text :
- https://doi.org/10.1016/j.cmet.2023.12.006