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Tools for assembling the cell: Towards the era of cell structural bioinformatics.

Authors :
Hu M
Zhang X
Latham A
Šali A
Ideker T
Lundberg E
Source :
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing [Pac Symp Biocomput] 2024; Vol. 29, pp. 661-665.
Publication Year :
2024

Abstract

Cells consist of large components, such as organelles, that recursively factor into smaller systems, such as condensates and protein complexes, forming a dynamic multi-scale structure of the cell. Recent technological innovations have paved the way for systematic interrogation of subcellular structures, yielding unprecedented insights into their roles and interactions. In this workshop, we discuss progress, challenges, and collaboration to marshal various computational approaches toward assembling an integrated structural map of the human cell.

Details

Language :
English
ISSN :
2335-6936
Volume :
29
Database :
MEDLINE
Journal :
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Publication Type :
Academic Journal
Accession number :
38160316