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[TUMOR-LIKE EFFECT AS INITIAL PRESENTATION OF PEDIATRIC MULTIPLE SCLEROSIS].

Authors :
Menascu S
Pollak A
Warszawer Y
Bar-On S
Messika Gold N
Freed A
Dreyer Alster S
Vered D
Miron S
Achiron A
Source :
Harefuah [Harefuah] 2023 Dec; Vol. 162 (10), pp. 660-665.
Publication Year :
2023

Abstract

Introduction: In both children and adults, magnetic resonance imaging of the brain in cases of multiple sclerosis (MS) has typical indications, where one of the key points for differentiating between demyelinating processes and place-taking processes is the fact that most of the lesions that appear in multiple sclerosis do not cause a mass effect or much edema around them. There are several uncommon subtypes of multiple sclerosis that can appear specifically in adolescents, presenting with a stormy clinical course and accompanied by brain lesions that resemble space-occupying lesions. These include Marburg disease, Balò's concentric sclerosis, and tumefactive MS. These unusual presentations raise the question regarding the ability to distinguish between neoplastic and demyelinating processes. In this article we present two case studies that illustrate this diagnostic dilemma and an accompanying literature review.

Details

Language :
Hebrew
ISSN :
0017-7768
Volume :
162
Issue :
10
Database :
MEDLINE
Journal :
Harefuah
Publication Type :
Academic Journal
Accession number :
38126150