Increased circulation of human adenovirus in 2023: an investigation of the circulating genotypes, upper respiratory viral loads, and hospital admissions in a large academic medical center.

Importance: The circulation of human adenoviruses (HAdV) increased in 2023. In this manuscript, we show that HAdV-B3 was predominant in 2023 in a cohort characterized by the Johns Hopkins Hospital System. We also show that HAdV-B3 was associated with an increase in viral loads in respiratory samples and provide a correlation with the clinical presentations and outcomes.
Competing Interests: H.M. has research collaborations with Bio-Rad, Qiagen, and Hologic. H.M. serves on the advisory board for Seegene and as a consultant for BD Diagnostics. H.M. received honoraria from Bio-Rad and BD Diagnostics.