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Eosinophil Distribution in Eosinophilic Esophagitis and its Impact on Disease Activity and Response to Treatment.
- Source :
-
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2024 Jul; Vol. 22 (7), pp. 1528-1530.e3. Date of Electronic Publication: 2023 Dec 16. - Publication Year :
- 2024
-
Abstract
- Although mostly accentuated in the distal esophagus, distribution of esophageal eosinophilia in eosinophilic esophagitis (EoE) seems to be nonuniform. <superscript>1</superscript> Disease extent has been associated with disease severity and disease progression in inflammatory bowel disease. <superscript>2,3</superscript> Whether the same holds true for EoE remains largely unknown. One recent EoE study looked at the distribution of eosinophilia, but without analyzing its potential association with treatment outcomes. <superscript>4</superscript> Here, we characterize the different inflammatory patterns of EoE and investigate their impact on disease presentation and disease outcome, with a particular focus on therapeutic response.<br /> (Copyright © 2024 AGA Institute. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Male
Treatment Outcome
Eosinophilic Esophagitis therapy
Eosinophils
Subjects
Details
- Language :
- English
- ISSN :
- 1542-7714
- Volume :
- 22
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
- Publication Type :
- Academic Journal
- Accession number :
- 38110063
- Full Text :
- https://doi.org/10.1016/j.cgh.2023.12.003