Back to Search
Start Over
Patient and Physician Perspectives of Systemic Lupus Erythematosus Flare: A Qualitative Study.
- Source :
-
The Journal of rheumatology [J Rheumatol] 2024 May 01; Vol. 51 (5), pp. 488-494. Date of Electronic Publication: 2024 May 01. - Publication Year :
- 2024
-
Abstract
- Objective: Systemic lupus erythematosus (SLE) flares are associated with increased damage and decreased health-related quality of life. We hypothesized that there is discordance between physicians' and patients' views of SLE flare. In this study, we aimed to explore patient and physician descriptions of SLE flares.<br />Methods: We conducted a qualitative descriptive study using in-depth interviews with a purposeful sample of patients with SLE (who met 1997 American College of Rheumatology or Systemic Lupus International Collaborating Clinics criteria) and practicing rheumatologists. Interviews were audio-recorded, transcribed, and analyzed using applied thematic analysis.<br />Results: Forty-two patient participants with SLE, representing a range of SLE activity, completed interviews. The majority described flare symptoms as joint pain, fatigue, and skin issues lasting several days. Few included objective signs or laboratory measures, when available, as features of flare. We interviewed 13 rheumatologists from 10 academic and 3 community settings. The majority defined flare as increased or worsening SLE disease activity, with slightly more than half requiring objective findings. Around half of the rheumatologists included fatigue, pain, or other patient-reported symptoms.<br />Conclusion: Patients and physicians described flare differently. Participants with SLE perceived flares as several days of fatigue, pain, and skin issues. Providers defined flares as periods of increased clinical SLE activity. Our findings suggest the current definition of flare may be insufficient to integrate both perceptions. Further study is needed to understand the pathophysiology of patient flares and the best way to incorporate patients' perspectives into clinical assessments.<br /> (Copyright © 2024 by the Journal of Rheumatology.)
- Subjects :
- Humans
Female
Adult
Male
Middle Aged
Symptom Flare Up
Fatigue etiology
Severity of Illness Index
Rheumatologists psychology
Physicians psychology
Aged
Interviews as Topic
Lupus Erythematosus, Systemic psychology
Lupus Erythematosus, Systemic physiopathology
Lupus Erythematosus, Systemic diagnosis
Qualitative Research
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1499-2752
- Volume :
- 51
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The Journal of rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 38101916
- Full Text :
- https://doi.org/10.3899/jrheum.2023-0721